The quality of life and longevity for patients with Chronic Granulomatous Disease (CGD) has improved dramatically over the last 50 years with knowledge of the phagocytic cell abnormality and appreciation of the need for early, aggressive antibiotic therapy when infections occur.

The great majority of children with CGD can expect to live well into adulthood, and many adult patients with CGD have jobs, get married and have children. However, patients with CGD remain at significant risk for infection throughout life. They must take their prophylactic drugs, remain cautious, and be vigilant to seek early diagnosis and treatment for possible infections.

Hospitalizations may be required for patients with CGD to locate sites and causes of infections. Intravenous antibiotics may be needed for serious infections. Prophylactic antibiotics increase healthy periods.

Serious infections tend to occur less frequently when patients reach their teenage years. Again, it must be emphasized that many patients with CGD complete high school, attend college, and are carrying on relatively normal lives.13

13 http://primaryimmune.org/wp-content/uploads/2011/04/Chronic-Granulomatous-Disease1.pdf

Source: Immune Deficiency Foundation Patient & Family Handbook for Primary Immunodeficiency Diseases FIFTH EDITION Copyright 2013 by Immune Deficiency Foundation, USA. This page contains general medical information which cannot be applied safely to any individual case. Medical knowledge and practice can change rapidly. Therefore, this page should not be used as a substitute for professional medical advice